ACETONE
MSDS Number: A0446 --- Effective Date: 04/09/98
1. Product Identification
Synonyms: Dimethylketone; 2-propanone; dimethylketal
CAS No.: 67-64-1
Molecular Weight: 58.08
Chemical
Formula: (CH3)2CO
Product Codes:
J.T. Baker: 5356, 5580,
5805, 9001, 9002, 9003, 9004, 9005, 9006, 9007, 9008, 9009, 9010, 9015, 9036,
9125, 9254, 9271, A134
Mallinckrodt: 0018, 2432, 2435, 2437, 2438, 2440,
2443, 2445, 2850, H451, H580, H981
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Acetone 67-64-1 99 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
DANGER! EXTREMELY FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH
FIRE. HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. AFFECTS CENTRAL NERVOUS SYSTEM.
J.T. Baker
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 1 - Slight
Flammability Rating: 4 - Extreme (Flammable)
Reactivity Rating: 2 - Moderate
Contact Rating: 1 - Slight
Lab
Protective Equip: GOGGLES; LAB COAT; VENT HOOD; PROPER GLOVES; CLASS B
EXTINGUISHER
Storage Color Code: Red (Flammable)
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Potential Health Effects
----------------------------------
Inhalation:
Inhalation of vapors irritates the respiratory
tract. May cause coughing, dizziness, dullness, and headache. Higher
concentrations can produce central nervous system depression, narcosis, and
unconsciousness.
Ingestion:
Swallowing small amounts is not
likely to produce harmful effects. Ingestion of larger amounts may produce
abdominal pain, nausea and vomiting. Aspiration into lungs can produce severe
lung damage and is a medical emergency. Other symptoms are expected to
parallel inhalation.
Skin Contact:
Irritating due to defatting
action on skin. Causes redness, pain, drying and cracking of the skin.
Eye Contact:
Vapors are irritating to the eyes. Splashes may
cause severe irritation, with stinging, tearing, redness and pain.
Chronic Exposure:
Prolonged or repeated skin contact may
produce severe irritation or dermatitis.
Aggravation of Pre-existing
Conditions:
Use of alcoholic beverages enhances toxic effects.
Exposure may increase the toxic potential of chlorinated hydrocarbons, such as
chloroform, trichloroethane.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Ingestion:
Aspiration hazard. If swallowed, vomiting
may occur spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head
below hips to prevent aspiration into lungs. Never give anything by mouth to
an unconscious person. Call a physician immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes.
Remove contaminated clothing and shoes. Get medical attention. Wash clothing
before reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting upper and lower eyelids occasionally. Get medical attention.
5. Fire Fighting Measures
Fire:
Flash point: -20C (-4F) CC
Autoignition
temperature: 465C (869F)
Flammable limits in air % by volume:
lel: 2.5;
uel: 12.8
Extremely Flammable Liquid and Vapor! Vapor may cause flash fire.
Explosion:
Above flash point, vapor-air mixtures are explosive
within flammable limits noted above. Vapors can flow along surfaces to distant
ignition source and flash back. Contact with strong oxidizers may cause fire.
Sealed containers may rupture when heated. This material may produce a
floating fire hazard. Sensitive to static discharge.
Fire Extinguishing
Media:
Dry chemical, alcohol foam or carbon dioxide. Water may be
ineffective. Water spray may be used to keep fire exposed containers cool,
dilute spills to nonflammable mixtures, protect personnel attempting to stop
leak and disperse vapors.
Special Information:
In the event of
a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or
other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! If a leak or spill has not ignited, use water spray to disperse the
vapors, to protect personnel attempting to stop leak, and to flush spills away
from exposures. US Regulations (CERCLA) require reporting spills and releases
to soil, water and air in excess of reportable quantities. The toll free
number for the US Coast Guard National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB(R) solvent adsorbent is recommended for spills of
this product.
7. Handling and Storage
Protect against physical damage. Store in a cool, dry
well-ventilated location, away from any area where the fire hazard may be
acute. Outside or detached storage is preferred. Separate from incompatibles.
Containers should be bonded and grounded for transfers to avoid static sparks.
Storage and use areas should be No Smoking areas. Use non-sparking type tools
and equipment, including explosion proof ventilation. Containers of this
material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Acetone:
-OSHA Permissible
Exposure Limit (PEL):
1000 ppm (TWA)
-ACGIH Threshold Limit Value
(TLV):
500 ppm (TWA), 750 ppm (STEL) A4 - not classifiable as a human
carcinogen
Ventilation System:
A system of local and/or general
exhaust is recommended to keep employee exposures below the Airborne Exposure
Limits. Local exhaust ventilation is generally preferred because it can
control the emissions of the contaminant at its source, preventing dispersion
of it into the general work area. Please refer to the ACGIH document,
Industrial Ventilation, A Manual of Recommended Practices, most recent
edition, for details.
Personal Respirators (NIOSH Approved):
If
the exposure limit is exceeded, a half-face organic vapor respirator may be
worn for up to ten times the exposure limit or the maximum use concentration
specified by the appropriate regulatory agency or respirator supplier,
whichever is lowest. A full-face piece organic vapor respirator may be worn up
to 50 times the exposure limit or the maximum use concentration specified by
the appropriate regulatory agency or respirator supplier, whichever is lowest.
For emergencies or instances where the exposure levels are not known, use a
full-face piece positive-pressure, air-supplied respirator. WARNING:
Air-purifying respirators do not protect workers in oxygen-deficient
atmospheres.
Skin Protection:
Wear impervious protective
clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact.
Eye Protection:
Use
chemical safety goggles and/or a full face shield where splashing is possible.
Maintain eye wash fountain and quick-drench facilities in work area.
9. Physical and Chemical Properties
Appearance:
Clear, colorless, volatile liquid.
Odor:
Fragrant, mint-like
Solubility:
Miscible
in all proportions in water.
Specific Gravity:
0.79 @ 20C/4C
pH:
No information found.
% Volatiles by volume @ 21C
(70F):
100
Boiling Point:
56.5C (133F) @ 760 mm Hg
Melting Point:
-95C (-139F)
Vapor Density (Air=1):
2.0
Vapor Pressure (mm Hg):
400 @ 39.5C (104F)
Evaporation Rate (BuAc=1):
ca. 7.7
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Carbon dioxide and
carbon monoxide may form when heated to decomposition.
Hazardous
Polymerization:
Will not occur.
Incompatibilities:
Concentrated nitric and sulfuric acid mixtures, oxidizing materials,
chloroform, alkalis, chlorine compounds, acids, potassium t-butoxide.
Conditions to Avoid:
Heat, flames, ignition sources and
incompatibles.
11. Toxicological Information
Oral rat LD50: 5800 mg/kg; Inhalation rat LC50: 50,100mg/m3;
Irritation eye rabbit, Standard Draize, 20 mg severe; investigated as a
tumorigen, mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Acetone (67-64-1) No No None
12. Ecological Information
Environmental Fate:
When released into the soil, this
material is expected to readily biodegrade. When released into the soil, this
material is expected to leach into groundwater. When released into the soil,
this material is expected to quickly evaporate. When released into water, this
material is expected to readily biodegrade. When released to water, this
material is expected to quickly evaporate. This material has a log
octanol-water partition coefficient of less than 3.0. This material is not
expected to significantly bioaccumulate. When released into the air, this
material may be moderately degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material may be moderately
degraded by photolysis. When released into the air, this material is expected
to be readily removed from the atmosphere by wet deposition.
Environmental Toxicity:
This material is not expected to be
toxic to aquatic life. The LC50/96-hour values for fish are over 100 mg/l.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: ACETONE
Hazard Class: 3
UN/NA: UN1090
Packing Group: II
Information reported for
product/size: 350LB
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name: ACETONE
Hazard Class: 3.1
UN/NA: UN1090
Packing Group: II
Information reported for product/size: 350LB
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Acetone (67-64-1) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Acetone (67-64-1) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Acetone (67-64-1) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Acetone (67-64-1) 5000 U002 No
Chemical Weapons Convention: No TSCA 12(b): Yes CDTA: Yes
SARA 311/312: Acute: Yes Chronic: No Fire: Yes Pressure: No
Reactivity: No (Pure / Liquid)
Australian Hazchem Code: 2[Y]E
Poison
Schedule: No information found.
WHMIS:
This MSDS has been
prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the
CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 3
Reactivity: 0
Label Hazard Warning:
DANGER! EXTREMELY
FLAMMABLE LIQUID AND VAPOR. VAPOR MAY CAUSE FLASH FIRE. HARMFUL IF SWALLOWED
OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. AFFECTS
CENTRAL NERVOUS SYSTEM.
Label Precautions:
Keep away from heat,
sparks and flame.
Keep container closed.
Use only with adequate
ventilation.
Wash thoroughly after handling.
Avoid breathing
vapor.
Avoid contact with eyes, skin and clothing.
Label First
Aid:
Aspiration hazard. If swallowed, vomiting may occur
spontaneously, but DO NOT INDUCE. If vomiting occurs, keep head below hips to
prevent aspiration into lungs. Never give anything by mouth to an unconscious
person. Call a physician immediately. If inhaled, remove to fresh air. If not
breathing, give artificial respiration. If breathing is difficult, give
oxygen. In case of contact, immediately flush eyes or skin with plenty of
water for at least 15 minutes. Remove contaminated clothing and shoes. Wash
clothing before reuse. In all cases, get medical attention.
Product
Use:
Laboratory Reagent.
Revision Information:
MSDS
Section(s) changed since last revision of document include: 8.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)