METHYLENE CHLORIDE
MSDS Number: M4420 --- Effective Date: 06/30/98
1. Product Identification
Synonyms: MC; Dichloromethane (DCM); Methylene dichloride;
Methylene bichloride; Methane dichloride
CAS No.: 75-09-2
Molecular Weight: 84.93
Chemical Formula: CH2Cl2
Product Codes: 9264, 9266, 9295, 9315, 9324, 9329, 9330, 9341,
9348, 9350, 9965, Q480
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Methylene Chloride 75-09-2 > 99% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED, INHALED OR ABSORBED THROUGH SKIN.
AFFECTS CENTRAL NERVOUS SYSTEM, LIVER, CARDIOVASCULAR SYSTEM, AND BLOOD.
CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT. SUSPECT CANCER HAZARD.
MAY CAUSE CANCER. Risk of cancer depends on level and duration of exposure.
J.T. Baker SAF-T-DATA(tm) Ratings (Provided here
for your convenience)
-----------------------------------------------------------------------------------------------------------
Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 1 -
Slight
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT
HOOD; PROPER GLOVES
Storage Color Code: Blue (Health)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to respiratory tract.
Has a strong narcotic effect with symptoms of mental confusion,
light-headedness, fatigue, nausea, vomiting and headache. Causes formation of
carbon monoxide in blood which affects cardiovascular system and central
nervous system. Continued exposure may cause increased light-headedness,
staggering, unconsciousness, and even death. Exposure may make the symptoms of
angina (chest pains) worse.
Ingestion:
May cause irritation of
the gastrointestinal tract with vomiting. If vomiting results in aspiration,
chemical pneumonia could follow. Absorption through gastrointestinal tract may
produce symptoms of central nervous system depression ranging from light
headedness to unconsciousness.
Skin Contact:
Causes irritation,
redness and pain. Prolonged contact can cause burns. Liquid degreases the
skin. May be absorbed through skin.
Eye Contact:
Vapors can
cause eye irritation. Contact can produce pain, inflammation and temporal eye
damage.
Chronic Exposure:
Can cause headache, mental confusion,
depression, liver effects, kidney effects, bronchitis, loss of appetite,
nausea, lack of balance, and visual disturbances. Can cause dermatitis upon
prolonged skin contact. Methylene chloride may cause cancer in humans.
Aggravation of Pre-existing Conditions:
Persons with
pre-existing skin disorders, eye problems, impaired liver, kidney, respiratory
or cardiovascular function may be more susceptible to the effects of this
substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING.
Give large quantities of water. Never give anything by mouth to an unconscious
person. Get medical attention immediately.
Skin Contact:
Immediately flush skin with plenty of soap and water for at least 15
minutes while removing contaminated clothing and shoes. Get medical attention.
Wash clothing before reuse. Thoroughly clean shoes before reuse.
Eye
Contact:
Immediately flush eyes with plenty of water for at least 15
minutes, lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Autoignition temperature: 556C
(1033F)
Flammable limits in air % by volume:
lel: 12; uel:
23
Forms flammable vapor-air mixtures above 100C (212F).
Explosion:
Concentrated can be ignited by a high intensity
ignition source. Vapor may form flammable mixture in atmosphere that contains
a high percentage of oxygen. Sealed containers may rupture when heated.
Fire Extinguishing Media:
Dry chemical, foam or carbon dioxide.
Water spray may be used to keep fire exposed containers cool.
Special
Information:
In the event of a fire, wear full protective clothing and
NIOSH-approved self-contained breathing apparatus with full facepiece operated
in the pressure demand or other positive pressure mode. Combustion by-products
include phosgene and hydrogen chloride gases. Structural firefighters'
clothing provides only limited protection to the combustion products of this
material.
6. Accidental Release Measures
Ventilate area of leak or spill. Remove all sources of ignition.
Wear appropriate personal protective equipment as specified in Section 8.
Isolate hazard area. Keep unnecessary and unprotected personnel from entering.
Contain and recover liquid when possible. Use non-sparking tools and
equipment. Collect liquid in an appropriate container or absorb with an inert
material (e. g., vermiculite, dry sand, earth), and place in a chemical waste
container. Do not use combustible materials, such as saw dust. Do not flush to
sewer! US Regulations (CERCLA) require reporting spills and releases to soil,
water and air in excess of reportable quantities. The toll free number for the
US Coast Guard National Response Center is (800) 424-8802.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry,
ventilated area. Protect against physical damage. Isolate from any source of
heat or ignition. Outside or detached storage is recommended. Containers of
this material may be hazardous when empty since they retain product residues
(vapors, liquid); observe all warnings and precautions listed for the product.
To minimize decomposition, all storage containers should be galvanized or
lined with a phenolic coating. This material may corrode plastic and rubber.
Wear special protective equipment (Sec. 8) for maintenance break-in or where
exposures may exceed established exposure levels. Wash hands, face, forearms
and neck when exiting restricted areas. Shower, dispose of outer clothing,
change to clean garments at the end of the day. Avoid cross-contamination of
street clothes. Wash hands before eating and do not eat, drink, or smoke in
workplace. Odor Threshold: 205 - 307 ppm. The odor threshold only serves as a
warning of exposure; not smelling it does not mean you are not being exposed.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
Methylene Chloride
(Dichloromethane):
- OSHA Permissible Exposure Limit (PEL) -
25 ppm
(TWA), 125 ppm (STEL), 12.5 ppm (8-hour TWA - Action Level)
- ACGIH
Threshold Limit Value (TLV) -
50 ppm (TWA), A2 - suspected human
carcinogen.
Ventilation System:
A system of local and/or
general exhaust is recommended to keep employee exposures below the Airborne
Exposure Limits. Local exhaust ventilation is generally preferred because it
can control the emissions of the contaminant at its source, preventing
dispersion of it into the general work area. Please refer to the ACGIH
document, Industrial Ventilation, A Manual of Recommended Practices,
most recent edition, for details.
Personal Respirators (NIOSH
Approved):
If the exposure limit is exceeded, wear a supplied air,
full-facepiece respirator, airlined hood, or full-facepiece self-contained
breathing apparatus. The cartridges recommended for this material have a
predicted service of less than 30 minutes at concentrations of ten times (10x)
the exposure limits. Actual service life will vary considerbly, depending on
concentration levels, temperature, humidity, and work rate. This substance has
poor warning properties.
Skin Protection:
Wear impervious
protective clothing, including boots, gloves, lab coat, apron or coveralls, as
appropriate, to prevent skin contact. Neoprene is a recommended material for
personal protective equipment. Natural rubber and polyvinyl chloride ARE NOT
recommended materials for personal protective equipment.
Eye
Protection:
Use chemical safety goggles and/or a full face shield
where splashing is possible. Maintain eye wash fountain and quick-drench
facilities in work area.
Other Control Measures:
Do not use
closed circuit rebreathing system employing soda lime or other carbon dioxide
absorber because of formation of toxic compounds capable of producing cranial
nerve paralysis. See OSHA Standard for medical surveillance, record keeping,
and reporting requirements for methylene chloride (29 CFR 1910.1052).
9. Physical and Chemical Properties
Appearance:
Clear, colorless liquid.
Odor:
Chloroform-like odor.
Solubility:
1.32 gm/100 gm water @
20C.
Specific Gravity:
1.33 @ 15C/4C
pH:
No
information found.
% Volatiles by volume @ 21C (70F):
100
Boiling Point:
39.8C (104F)
Melting Point:
-97C
(-143F)
Vapor Density (Air=1):
2.9
Vapor Pressure (mm
Hg):
350 @ 20C (68F)
Evaporation Rate (BuAc=1):
27.5
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Emits highly toxic
fumes of phosgene when heated to decomposition. Decomposes in a flame or hot
surface to form toxic gas phosgene and corrosive mists of hydrochloric acid.
Carbon dioxide and carbon monoxide may form when heated to decomposition.
Hazardous Polymerization:
Will not occur.
Incompatibilities:
Strong oxidizers, strong caustics, plastics,
rubber, nitric acid, water + heat, and chemically active metals, such as
aluminum and magnesium powder, sodium, potassium, and lithium. Avoid contact
with open flames and electrical arcs. Liquid methylene chloride will attack
some forms of plastics, rubber, and coatings.
Conditions to Avoid:
Moisture, heat, flames, ignition sources and incompatibles.
11. Toxicological Information
Toxicological Data:
Dichloromethane: Oral rat LD50:
1600 mg/kg; inhalation rat LC50: 52 gm/m3; investigated as a tumorigen,
mutagen, reproductive effector.
Reproductive Toxicity:
Dichloromethane has been linked to spontaneous abortions in humans.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Methylene Chloride (75-09-2) No Yes 2B
12. Ecological Information
Environmental Fate:
When released into the soil, this
material may leach into groundwater. When released into the soil, this
material is expected to quickly evaporate. When released into water, this
material may biodegrade to a moderate extent. When released to water, this
material is expected to quickly evaporate. This material has a log
octanol-water partition coefficient of less than 3.0. This material is not
expected to significantly bioaccumulate. When released into the air, this
material may be moderately degraded by reaction with photochemically produced
hydroxyl radicals. When released into the air, this material is expected to
have a half-life of greater than 30 days. When released into the air, this
material may be removed from the atmosphere to a moderate extent by wet
deposition.
Environmental Toxicity:
The LC50/96-hour values for
fish are over 100 mg/l. This material is not expected to be toxic to aquatic
life.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
handled as hazardous waste and sent to a RCRA approved incinerator or disposed
in a RCRA approved waste facility. Processing, use or contamination of this
product may change the waste management options. State and local disposal
regulations may differ from federal disposal regulations. Dispose of container
and unused contents in accordance with federal, state and local requirements.
14. Transport Information
Domestic (Land, D.O.T.)
-----------------------
Proper Shipping Name: DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported
for product/size: 52L
International (Water, I.M.O.)
-----------------------------
Proper Shipping Name:
DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported for product/size: 52L
International (Air, I.C.A.O.)
-----------------------------
Proper Shipping Name: DICHLOROMETHANE
Hazard Class: 6.1
UN/NA: UN1593
Packing Group: III
Information reported
for product/size: 52L
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Methylene Chloride (75-09-2) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Methylene Chloride (75-09-2) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Methylene Chloride (75-09-2) No No Yes No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Methylene Chloride (75-09-2) 1000 U080 No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Liquid)
WARNING:
THIS PRODUCT CONTAINS A CHEMICAL(S) KNOWN TO
THE STATE OF CALIFORNIA TO CAUSE CANCER.
Australian Hazchem
Code: 2Z
Poison Schedule: S5
WHMIS:
This MSDS
has been prepared according to the hazard criteria of the Controlled Products
Regulations (CPR) and the MSDS contains all of the information required by the
CPR.
16. Other Information
NFPA Ratings: Health: 2 Flammability: 1
Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF
SWALLOWED, INHALED OR ABSORBED THROUGH SKIN. AFFECTS CENTRAL NERVOUS SYSTEM,
LIVER, CARDIOVASCULAR SYSTEM, AND BLOOD. CAUSES IRRITATION TO SKIN, EYES AND
RESPIRATORY TRACT. SUSPECT CANCER HAZARD. MAY CAUSE CANCER. Risk of cancer
depends on level and duration of exposure.
Label Precautions:
Do not breathe vapor.
Keep container closed.
Use only with adequate
ventilation.
Wash thoroughly after handling.
Keep away from heat and
flame.
Do not get in eyes, on skin, or on clothing.
Label First
Aid:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of
water. Never give anything by mouth to an unconscious person. If inhaled,
remove to fresh air. If not breathing, give artificial respiration. If
breathing is difficult, give oxygen. In case of contact, immediately flush
eyes or skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Wash clothing before reuse. In all cases, get
medical attention.
Product Use:
Laboratory Reagent.
Revision Information:
MSDS Section(s) changed since last
revision of document include: 1, 2.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)