UREA
MSDS Number: U4725 --- Effective Date: 11/17/99
1. Product Identification
Synonyms: Carbamide resin; Isourea; Carbonyl diamide;
Carbonyldiamine
CAS No.: 57-13-6
Molecular Weight: 60.06
Chemical Formula: (NH2)2CO
Product Codes:
J.T.
Baker: 4111, 4203, 4204, 4206, 5594, 5607
Mallinckrodt: 3192, 7729, 7816,
8642, 8644, 8647, 8648
2. Composition/Information on Ingredients
Ingredient CAS No Percent Hazardous
--------------------------------------- ------------ ------- ---------
Urea 57-13-6 99 - 100% Yes
3. Hazards Identification
Emergency Overview
--------------------------
WARNING! HARMFUL IF SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN,
EYES AND RESPIRATORY TRACT.
J.T. Baker
SAF-T-DATA(tm) Ratings (Provided here for your convenience)
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Health Rating: 0 - None
Flammability Rating: 1 - Slight
Reactivity
Rating: 0 - None
Contact Rating: 1 - Slight
Lab Protective Equip:
GOGGLES; LAB COAT
Storage Color Code: Orange (General Storage)
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Potential Health Effects
----------------------------------
Inhalation:
Causes irritation to the respiratory tract.
Symptoms may include coughing, shortness of breath. May be absorbed into the
bloodstream with symptoms similar to ingestion.
Ingestion:
Causes irritation to the gastrointestinal tract. Symptoms may include
nausea, vomiting and diarrhea. May also cause headache, confusion and
electrolyte depletion.
Skin Contact:
Causes irritation to skin.
Symptoms include redness, itching, and pain.
Eye Contact:
Causes irritation, redness, and pain.
Chronic Exposure:
A
study of 67 workers in an environment with high airborne concentrations of
urea found a high incidence of protein metabolism disturbances, moderate
emphysema, and chronic weight loss.
Aggravation of Pre-existing
Conditions:
Supersensitive individuals with skin or eye problems,
kidney impairment or asthmatic condition should have physician's approval
before exposure to urea dust.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give
artificial respiration. If breathing is difficult, give oxygen. Get medical
attention.
Ingestion:
Induce vomiting immediately as directed
by medical personnel. Never give anything by mouth to an unconscious person.
Get medical attention.
Skin Contact:
Immediately flush skin
with plenty of water for at least 15 minutes while removing contaminated
clothing and shoes. Wash clothing before reuse. Thoroughly clean shoes before
reuse. Get medical attention if symptoms occur.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes,
lifting lower and upper eyelids occasionally. Get medical attention
immediately.
5. Fire Fighting Measures
Fire:
Not considered to be a fire hazard.
Explosion:
Reactions with incompatibles may pose an explosion
hazard.
Fire Extinguishing Media:
Use any means suitable for
extinguishing surrounding fire.
Special Information:
In the
event of a fire, wear full protective clothing and NIOSH-approved
self-contained breathing apparatus with full facepiece operated in the
pressure demand or other positive pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal
protective equipment as specified in Section 8. Spills: Sweep up and
containerize for reclamation or disposal. Vacuuming or wet sweeping may be
used to avoid dust dispersal.
7. Handling and Storage
Keep in a tightly closed container, stored in a cool, dry,
ventilated area. Protect against physical damage. Isolate from incompatible
substances. Containers of this material may be hazardous when empty since they
retain product residues (dust, solids); observe all warnings and precautions
listed for the product.
8. Exposure Controls/Personal Protection
Airborne Exposure Limits:
For Urea:
-AIHA Workplace
Environmental Exposure Limit (WEEL):
10 mg/m3, 8-hour TWA
Ventilation System:
A system of local and/or general exhaust is
recommended to keep employee exposures below the Airborne Exposure Limits.
Local exhaust ventilation is generally preferred because it can control the
emissions of the contaminant at its source, preventing dispersion of it into
the general work area. Please refer to the ACGIH document, Industrial
Ventilation, A Manual of Recommended Practices, most recent edition, for
details.
Personal Respirators (NIOSH Approved):
If the exposure
limit is exceeded, a half-face dust/mist respirator may be worn for up to ten
times the exposure limit or the maximum use concentration specified by the
appropriate regulatory agency or respirator supplier, whichever is lowest. A
full-face piece dust/mist respirator may be worn up to 50 times the exposure
limit, or the maximum use concentration specified by the appropriate
regulatory agency, or respirator supplier, whichever is lowest. For
emergencies or instances where the exposure levels are not known, use a
full-facepiece positive-pressure, air-supplied respirator. WARNING:
Air-purifying respirators do not protect workers in oxygen-deficient
atmospheres. If heat is involved, an ammonia/methylamine, dust/mist cartridge
may be necessary.
Skin Protection:
Wear protective gloves and
clean body-covering clothing.
Eye Protection:
Use chemical
safety goggles and/or full face shield where dusting or splashing of solutions
is possible. Maintain eye wash fountain and quick-drench facilities in work
area.
9. Physical and Chemical Properties
Appearance:
White crystals or white powder.
Odor:
Develops odor of ammonia.
Solubility:
Very
soluble in water.
Specific Gravity:
1.32 @ 20C/4C
pH:
7.2 (10% in water)
% Volatiles by volume @ 21C
(70F):
0
Boiling Point:
Decomposes.
Melting
Point:
132 - 135C (270 - 275F)
Vapor Density (Air=1):
No information found.
Vapor Pressure (mm Hg):
No
information found.
Evaporation Rate (BuAc=1):
No information
found.
10. Stability and Reactivity
Stability:
Stable under ordinary conditions of use and
storage.
Hazardous Decomposition Products:
Urea decomposes upon
heating and can form products including ammonia, oxides of nitrogen, cyanuric
acid, cyanic acid, biuret, carbon dioxide.
Hazardous
Polymerization:
Will not occur.
Incompatibilities:
Urea
reacts with calcium hypochlorite or sodium hypochlorite to form the explosive
nitrogen trichloride. It is incompatible with sodium nitrite, gallium
perchlorate, strong oxidizing agents (permanganate, dichromate, nitrate,
chlorine), phosphorus pentachloride, nitrosyl perchlorate, titanium
tetrachloride and chromyl chloride.
Conditions to Avoid:
Incompatibles.
11. Toxicological Information
Urea: Oral rat LD50: 8471 mg/kg. Investigated as a tumorigen,
mutagen, reproductive effector.
--------\Cancer Lists\------------------------------------------------------
---NTP Carcinogen---
Ingredient Known Anticipated IARC Category
------------------------------------ ----- ----------- -------------
Urea (57-13-6) No No None
12. Ecological Information
Environmental Fate:
When released to soil, this
material will hydrolyze into ammonium in a matter of days to several weeks.
When released into the soil, this material may leach into groundwater. When
released into water, this material may biodegrade to a moderate extent. When
released into water, this material is not expected to evaporate significantly.
This material has an experimentally-determined bioconcentration factor (BCF)
of less than 100. This material is not expected to significantly
bioaccumulate. When released into the air, this material is expected to be
readily degraded by reaction with photochemically produced hydroxyl radicals.
When released into the air, this material is expected to have a half-life of
less than 1 day.
Environmental Toxicity:
No information found.
13. Disposal Considerations
Whatever cannot be saved for recovery or recycling should be
managed in an appropriate and approved waste disposal facility. Processing,
use or contamination of this product may change the waste management options.
State and local disposal regulations may differ from federal disposal
regulations. Dispose of container and unused contents in accordance with
federal, state and local requirements.
14. Transport Information
Not regulated.
15. Regulatory Information
--------\Chemical Inventory Status - Part 1\---------------------------------
Ingredient TSCA EC Japan Australia
----------------------------------------------- ---- --- ----- ---------
Urea (57-13-6) Yes Yes Yes Yes
--------\Chemical Inventory Status - Part 2\---------------------------------
--Canada--
Ingredient Korea DSL NDSL Phil.
----------------------------------------------- ----- --- ---- -----
Urea (57-13-6) Yes Yes No Yes
--------\Federal, State & International Regulations - Part 1\----------------
-SARA 302- ------SARA 313------
Ingredient RQ TPQ List Chemical Catg.
----------------------------------------- --- ----- ---- --------------
Urea (57-13-6) No No No No
--------\Federal, State & International Regulations - Part 2\----------------
-RCRA- -TSCA-
Ingredient CERCLA 261.33 8(d)
----------------------------------------- ------ ------ ------
Urea (57-13-6) No No No
Chemical Weapons Convention: No TSCA 12(b): No CDTA: No
SARA 311/312: Acute: Yes Chronic: Yes Fire: No Pressure: No
Reactivity: No (Pure / Solid)
Australian Hazchem Code: No information found.
Poison Schedule: No information found.
WHMIS:
This
MSDS has been prepared according to the hazard criteria of the Controlled
Products Regulations (CPR) and the MSDS contains all of the information
required by the CPR.
16. Other Information
NFPA Ratings: Health: 1 Flammability: 0
Reactivity: 0
Label Hazard Warning:
WARNING! HARMFUL IF
SWALLOWED OR INHALED. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY TRACT.
Label Precautions:
Avoid breathing dust.
Keep container
closed.
Avoid contact with eyes, skin and clothing.
Use only with
adequate ventilation.
Wash thoroughly after handling.
Label First
Aid:
If swallowed, induce vomiting immediately as directed by medical
personnel. Never give anything by mouth to an unconscious person. In case of
contact, immediately flush eyes or skin with plenty of water for at least 15
minutes. Remove contaminated clothing and shoes. Wash clothing before reuse.
If inhaled, remove to fresh air. If not breathing, give artificial
respiration. If breathing is difficult, give oxygen. In all cases, get medical
attention.
Product Use:
Laboratory Reagent.
Revision
Information:
New 16 section MSDS format, all sections have been
revised.
Disclaimer:
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Mallinckrodt Baker, Inc. provides the information contained herein in
good faith but makes no representation as to its comprehensiveness or
accuracy. This document is intended only as a guide to the appropriate
precautionary handling of the material by a properly trained person using this
product. Individuals receiving the information must exercise their independent
judgment in determining its appropriateness for a particular purpose.
MALLINCKRODT BAKER, INC. MAKES NO REPRESENTATIONS OR WARRANTIES, EITHER
EXPRESS OR IMPLIED, INCLUDING WITHOUT LIMITATION ANY WARRANTIES OF
MERCHANTABILITY, FITNESS FOR A PARTICULAR PURPOSE WITH RESPECT TO THE
INFORMATION SET FORTH HEREIN OR THE PRODUCT TO WHICH THE INFORMATION REFERS.
ACCORDINGLY, MALLINCKRODT BAKER, INC. WILL NOT BE RESPONSIBLE FOR DAMAGES
RESULTING FROM USE OF OR RELIANCE UPON THIS INFORMATION.
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Prepared by: Strategic Services Division
Phone Number: (314)
539-1600 (U.S.A.)